|Place of Origin:||China|
|Model Number:||Natural Extract|
|Minimum Order Quantity:||1KG|
|Packaging Details:||DRUM, CARTON|
|Payment Terms:||L/C, D/A, D/P, T/T, Western Union, MoneyGram|
|Supply Ability:||1000 TONS PER MONTH|
|Part:||Root||Extraction Type:||Solvent Extraction|
|Product Name:||Bio Fisetin||Active Ingredient:||Fisetin|
|Testing Method:||HPLC||Color:||Yellow Powder|
Anti Oxidant Bio Fisetin,
Anti Tumor Bio Fisetin,
Pharmaceutical Bio Fisetin
Natural Herbal Extracts Anti-Oxidant And Anti-Tumor Bio Fisetin
1. Introduction of Bio Fisetin
Fisetin is a kind of flavonoids, hardly soluble in water, carbon tetrachloride and petroleum ether, easily soluble in solvents such as acetone, acetic acid, etc. It is widely found in fruits and vegetables such as strawberries, apples, onions, cucumbers, and has a wide range of sources. , Cheap and easy to obtain, has a wide range of pharmacological activities, such as anti-inflammatory, anti-oxidation, anti-coagulation, anti-thrombosis, antispasmodic, treatment of diabetic kidney injury, etc. In recent years, studies have found that lacustrine can play an anti-tumor effect by inhibiting tumor cell proliferation and signal transduction pathways, and inducing tumor cell apoptosis. Therefore, it has received increasing attention. However, this ingredient has shortcomings such as insoluble in water and low bioavailability, which limits its further development and clinical application. At present, the research on fischerin mainly focuses on pharmacological activity, mechanism of action, extraction process, etc. There are few reports on related dosage forms. In recent years, researchers have tried to improve the solubility, bioavailability, and anti-tumor effects of qixanthin liposomes and nanomicelles. For example, the preparation of qixanthin liposomes can be significantly improved after intraperitoneal injection. Improve its solubility and bioavailability, and when conducting anti-tumor activity experiments in tumor-bearing mice, it was found that compared with APIs, low-dose liposomes can significantly increase the anti-tumor effect; preparation of yuxanthin micelles can increase its solubility And anti-tumor effect.
2. Parameters of Bio Fisetin
[Alias] C.I. 75620; C.I. Natural Brown 1; Fisetin; 3,3,4,7-Tetrahydroxyflavone; 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one
[Molecular weight] 286.23
[CAS NO] 528-48-3
[Detection method] HPLC ≥ 98%
[Specification] 10mg 20mg 100mg 500mg 1g (can be packed according to customer's demand)
[Character] the product is yellow needle crystal
[Function and use] this product is used for content determination.
[Extraction source] Rhus succedanea L. belongs to the family lacqueraceae
[Physical properties] yellow needle like crystal (dilute ethanol), melting point 330 ℃ (decomposition). Soluble in ethanol, acetone and acetic acid. It is almost insoluble in water, ether, benzene, chloroform and petroleum ether. Melting point 348 ℃, bright yellow fine needle crystal, melting point ＞ 300 ℃
3. Functions of Bio Fisetin
Bio fisetin has anti-oxidant, anti-inflammatory and neuroprotective pharmacological characteristics.
1.It can play a role in inducing tumor cell apoptosis, influencing tumor cell signal transduction pathways, inhibiting tumor cell proliferation, and inhibiting tumor cell migration and invasion. Anti-tumor effect;
2.Studies have shown that iochlavin can also exert an antidepressant effect by inhibiting the monoamine oxidase of the serotonin and norepinephrine system;
3.It has obvious protective and repairing effects on liver damage caused by hepatitis;
4.It can significantly improve the activity of immune cells . The Proceedings of the American Academy of Sciences reported that lacustrine can stimulate signal pathways and improve long-term memory;
5.It also has the effect of inhibiting aflatoxin cytotoxicity.
4. Application of Bio Fisetin
Mainly used in the medical field.
6. Display of Bio Fisetin